Microvascular Tissue Oximetry


Microvascular Tissue Oximetry utilizes Resonance Raman Spectroscopy (RSS) to measure tissue oxygenation from the inside of the patient’s cheek. RSS is a novel optical technique that provides a precise, quantitative chemical fingerprint of how well tissues are being oxygenated.

Value Proposition

Resonance Raman Spectroscopy (RSS) is resistant to interference and provides a precise, quantitative chemical fingerprint of how well tissues are being oxygenated, without the need for a central venous catheter. Using RSS in this device allows the sensor to be placed in the mouth and provide oxygenation information in seconds.

Competitive Advantage

  • The sensor can be placed in the mouth and provide oxygenation information in seconds, allowing for continuous monitoring or intermittent screening. 

Unique Features

  • Continuous Monitoring

  • Less Invasive

  • Quick Results

Licensing Information
Pendar Technologies in 2018

Principal Investigators
Kevin Ward, MD
Hakam Tiba, MD, MS
Kyle Gunnerson, MD

Intellectual Property
Patent Issued # US7113814

Solution Sheet
Download Solution Sheet (PDF)

Image courtesy of project team

MARKET OPPORTUNITY
Because of its non-invasive nature, RSS may serve as a faster, safer, and more cost-effective way to assess patient tissue oxygenation, aiding in the diagnosis and treatment of conditions such as sepsis, trauma, heart failure, and other critical states.

Contact Pendar Technologies for more information about investment and partnership opportunities.

Funding History

$2,999,754 in non-dilutive funding

  • 2018 $2,999,754 DOD

  • Substantial departmental, school and center based support

Funding Organizations


This work is supported by the Office of the Assistant Secretary of Defense for Health Affairs through the JPC-6 Combat Casualty Care / Defense Medical Research and Development Program under an assistance agreement from the U.S. Army Medical Research Activity, Award No. W81XWH-18-1-0078.

LicensedKate Murphy