Barreleye: A Decision Support Tool for TBI Care


Barreleye collects physiological data from various monitors and calculates clinically-relevant measures such as Shock Index and Pressure Reactivity Index continuously to gauge patient trajectory, predict potential adverse events and reduce the risk of secondary brain insult.

Value Proposition

The ability to continuously monitor, predict early, and detect potential causes for secondary brain insults after a Traumatic Brain Injury (TBI) greatly aids physicians and caregivers in providing preemptive intervention and treatment in order to preserve the stability of their patients. Barreleye provides high fidelity historical trend data and the patient’s predicted trajectory that are otherwise not available to clinicians. Barreleye collects physiological data from various monitors and calculates clinically-relevant measures such as Shock Index and Pressure Reactivity Index to gauge patient trajectory and predict potential adverse events. These measures were previously unusable due to complications in data collection.

Competitive Advantage

  • Non-Invasive

  • Alerts in Advance

  • Continuous Monitoring

  • Automatic Computations

Unique Features

  • Non-Invasive

  • Alerts in Advance

  • Continuous Monitoring

  • Automatic Computations of Shock Index (SI), Pressure Reactivity Index (PRx) and Cerebral Perfusion Pressure (CPP)

  • Utilizes a Signal Quality Index (SQI) to reduce or eliminate any “noisy” data

Licensing Information
FifthEye in 2018

Principal Investigators
Ashwin Belle, PhD
Kevin Ward, MD

Intellectual Property
Invention Disclosure # 7425, 7485, 2018-314, 2018-315

Solution Sheet
Download Solution Sheet (PDF)

Image courtesy of project team

MARKET OPPORTUNITY
Each year in the United States, an estimated 1.7 million people sustain a traumatic brain injury. Approximately 30% of all injury deaths are due, in part, to traumatic brain injuries. Barreleye can assist clinicians in deploying precision therapies prior to the onset of irreversible instability and injury, especially during the early critical hours of care.

Contact Fifth Eye for more information about investment and partnership opportunities.

Funding History

$83,489 in non-dilutive funding

  • 2017 $83,489 Massey Grand Challenge

  • Substantial departmental, school and center based support

Funding Organizations


LicensedKate Murphy